Bio-IT World Best Practices Award recognizes critical findings in studies of schizophrenia

The National Center for Resources of the genome (NCGR), with the SAS JMP Genomics pick up more information about the results of his research was published in 2009, Bio-IT World Best Practices Award for the genomics research of schizophrenia . NCGR non-profit research institute for the improvement of human health and nutrition, JMP Genomics offers in its process of downstream analysis pipeline Alpheus for the analysis to the next generation of sequencing data. Alpheus and mines are the imported data from several NCGR Illumina Genome Analyzer, while exports of data in the fields of genomics JMP for further analysis.

"With Illumina, Alpheus and JMP Genomics, we have a key in your hand, view the results, which will then be published," said Faye Schilkey, Associate Director of NCGR of New Mexico Genome Sequencing Center. "We have the samples sequenced Alpheus find most important genes, regions or polymorphisms to look, and then for JMP Genomics at the statistics."

In the next week published SAS JMP Genomics 4.0, the new statistical tools for monitoring the quality, standardization, and the discovery of the vast amount of genomics data. This all-in-one desktop solution dynamically links statistics with graphics enhanced for a full and comprehensive search results.

"With our help, such as NCGR JMP Genomics help analysts high Illumina sequencing data," said Russ Wolfinger, PhD, Scientific Director of the genomics and discovery of the SAS. "The close collaboration between SAS and NCGR helped lead the development of new tools for JMP Genomics 4, is sent to all users. For example, we have a NCGR of the application of the correlation process to cross-contamination associations between the frequencies of variant alleles summaries and freedom of expression."

The award was presented on Tuesday in the Bio-IT World Conference & Expo in Boston. NCGR has been nominated for the price of SAS, which is also in the past year as one of the winners.

NCGR is a non-profit research institute aimed at improving human health and nutrition through genome sequencing and analysis. NCGR CSPro ™ provides DNA sequencing with eight Illumina Genome Analyzer with software and services for the analysis of large sequencing, Alpheus system software.

JMP is a unit of SAS, founded in 1989, an interactive analysis of the discovery for desktop computers. John Sall, SAS co-founder and Executive Vice President, also at the helm of the company JMP.

SAS is the leader in analytical software and services company and the largest independent provider of business intelligence market. SAS 100 percent of Fortune 500 clients in the life sciences. By delivering innovative solutions in an integrated SAS supports customers in more than 45,000 sites improve performance and value-informed decisions are made faster. Since 1976 SAS has customers all over the world the opportunity to know.

Short stories shows that less can really be

I recently participated in the exercise of volumes of short stories, wherever I go. If I were on the metro or tram, with a medical appointment or in the queue for an indefinite period, or simply in the hope that some pages could reject me sleep, I have a story. But when I came with this short invention is ideal for situations such as this, I am increasingly convinced that they are simply perfect. It is possible that the youngest of the author of the article.

Without doubt one of the joyful discovery that I as a professional drive is the only pleasure, short stories. Not that I do not have - a long time I liked the stories by JD Salinger, William Trevor, John Cheever, James Joyce, Annie Proulx, and a few other select - it's just that they will never be the first to go, as fiction, I was looking . Without it, the stupid, I internalized the fact that short stories were in some way a lesser form of the invention expression, a kind of prosaic form of demo recordings in the studio, video films, the repetition of reality, a sketch on the way to a table. They were either in the novels of the embryo, or, as the writer created until they are ready for the real thing.

In this context, the modest and reassured me that I was not alone. Many writers are in the same way. Recently I met in the introduction to an end, is another collection of new messages to the American author Jay McInerney: "It is clear, I was also on the long, and my short stories - some of them at least d - repeatedly shown to be exercises to warming. "

Often, but not always. Sometimes, in the perception of itself and is difficult to continue. "I've always been more than a little intimidated by the new," then confesses McInerney. "Given the fact that even medium-sized and new - and even less the way Henry James describes as a loose baggy monsters - you can survive any number of wrong, boring and key figures from records, the story is much less generous. A good requires a perfect height and direction in exactly the form he has to burn a CD, gem-like flame. "

Take is six clock Do You Know Where You Are? Sample. This was one of McInerney's first attempt to form, and it was the sketch, or "warm-up exercise", which was the author of the first novel of urban yuppie of the 80s missing link Bright Lights, Big City. As a story, the first collection, it is said more than 12 pages in the book more than 200 We are in the forefront of a young, upper-Mobile Sybarite. It is after the end of alcohol and coke, which in the night, and it seems in the twilight flashing Manhattan with a view to another day shivering empty. It May, before the release, but even to us to decide. Everything we know is that his nostrils are suddenly hit seeps through the scent of freshly baked bread, baking and final act - the story at least - that's his jacket, a bag of fresh rolls. "Tear the bag open," are the last lines of history ", and the smell of warm dough is crashing on you. The first bite sticks in the throat and almost gag. They go slow. You have everything to learn again. "

Is it? Or will it just to go home, vomiting bread, the sick and to the awakening in another night of oblivion calculated? We are invited to beat the flame through the history in our pockets for the rest of the story in our own interpretation of what we read. If you ask me, is it six clock morning Do You Know Where You Are? is better than the novel, there was, because it forces me to write what the rest of the story or leave as it is. It calls my imagination as a kind of staff actively involved in the invention. The book tells me what happened, where the history of the recommendations.

McInerney graduated from the University of Syracuse by Raymond Carver and Tobias Wolff, two acknowledged masters of American short fiction, and this is a measure of the persistence of warm-up exercise in the mythology does not explain that these writers have to create him the conviction that the short stories are novels in preparation. Because when it comes to the mastery of form, particularly in the areas of economy, the vision and burning up with a stone similar to the flame, you do not much concentrated heat that Carver, a man may be the whole of the living nature of the shiny formica a kitchen table.

Carver collections like Where I'm Calling From, and what we Talk About When We Talk About Love are the cornerstone for the short history of art for their rough diamonds eloquent economy and accuracy. Perhaps more than at the end of the 20th Century, American writers, the end of the carvers the art of short fiction as an art of omission: that is what was not there that counts at the end, says the report, and it was closing the gap by the absence of suction, we calculated these images in the virtual co-creator of reality, they are limited. As readers, Carver knew how we work, and the pleasure of the effort for the fulfillment of the rooms is one of the largest in the playback of the invention provides.

In the best short film, feature film, the style and vision commingle in a way which is unique in form. This is also a pleasure, the high frequencies. Some years ago I visited with three volumes: The Complete Short Stories of Ernest Hemingway, Selected Stories by Alice Munro and stories of Vladimir Nabokov. I set them in rotation, through the reproduction of a story of the author, before they hand in the next book. The effect, as a reader, was a remarkable year. Not only I was able to improve the quality of the stories about himself - and not more than three authors from different unbelievable - I was surprised by the consistency of clay, I've met when I am rotating back into the world of writers . And that's the point: It is a world. Or three really: Munro is a place of tranquility, localized despair; Hemingway a strong limit for the examination of the evidence existential Nabokov Golden Hall of the distortion of the illusion of size and color.

It was the thing: If everyone lived and breathed history and frequented as a separate entity on its own initiative, it also has a rich about life if they believe in the context of other stories the author. It was the vitality of the reasons for the security of the author's voice. What is the novel, one thing a lot of hermetic, offers the promise immersion in another world. This is also true for the best new collection, but the world is something else. It is through the power and the ability of the author's voice, and there is life after the conversation between the voice and the questions remain for us to ask.

Argentex field discovered 12 new mineralized veins at Pinguino, Santa Cruz, Argentina

VANCOUVER- Argentex Mining Corporation is pleased to announce the results of a program of mapping the territory that was recently completed by the geologists of the company at Pinguino. A total of 14 line km veins were found in 12 new structures. The areas were selected for the survey based on a combination of anomalies of multi-element soil geochemistry, IP chargeability, magnetic and soil, and the extension of existing facilities, including Yvonne. One meter resolution Ikonos images was used as a basis for mapping and exploration.

Plotting of the veins on the property now cover a length of 74 km and the mineralization has been demonstrated the depth of drilling in 15 of the 47 sectors. The results of this recent include samples with values up to 2.5 grams per tonne, gold, lead and 10% exceeding 300 g / t silver, respectively.

"On the basis of geological interpretation, mapping and sampling by our team of field, we can now detect subtle expression of the surface successfully Penguin sulphide veins that are not identified by the previous owners," said Ken Hicks, President of Argentex . The first results of our field program in 2009 are very encouraging and has several new targets from which to develop additional mineralization at depth and along strike. We are finishing our first National Instruments 43-101-compliant resource status estimate, which will be the next important step in the development of society. "

Scientists discover genetic defect model to predict the success drug against cancer

A model of genetic defects in tumors may indicate whether the patients with ovarian cancer respond to chemotherapy drugs before starting treatment, a British study shows cancer research published in the Proceedings of the National Academy of Sciences' today (Monday).

The researchers studied the gene expression patterns that indicate a high level of abnormal chromosomes or chromosomal instability (CIN) in cancer.

They have shown that a subset of these genes are required by CIN tumor cells to survive - and that these cells have higher levels of these genes, making them more resistant to a drug called paclitaxel.

They then sought to determine if it can help doctors determine which patients CIN are more likely to respond to the chemotherapy drugs paclitaxel and carboplatin in a clinical study of patients with ovarian cancer.

Patients with high levels of CIN gene product are more resistant to paclitaxel.

In essence, patients with high levels of CIN responded to carboplatin - another commonly used drug against ovarian cancer.

In contrast, tumors with a low level of CIN were resistant to carboplatin, but responded to paclitaxel.

The researchers believe that clinical trials for the INC - which can be identified by dye stained cells under a microscope - could be available within five years, saving patients from ineffective chemotherapy and lead to personalized treatment.

Lead author Dr Julian downwards, based at Cancer Research UK London Research Institute, said: "Our work suggests that resistance to paclitaxel is motivated by various deficiencies found in tumor cells leading to abnormal cell division cancer. These changes also in May tumors more sensitive to carboplatin treatment. "

Each year in the United Kingdom, more than 6600 cases of ovarian cancer are diagnosed and approximately 4,500 women die of this disease.

Principal co-author Dr James Brenton, headquartered in the United Kingdom, Cancer Research Research Institute of Cambridge and ovarian cancer in clinical Addenbrooke's Hospital, said: "All ovarian cancer patients are treated with carboplatin, but most of those who are more aggressive cancer treated with paclitaxel as well. We do not know which patients will benefit from further paclitaxel, it is very important that we develop tests to better select the right drugs for patients. "

Lead author Dr. Charles Swanton, based at Cancer Research UK London Research Institute and the Royal Marsden Hospital, said: "So far it has been difficult to predict which patients will benefit in May of chemotherapeutic drugs before each treatment. We hope that simple test on the basis of these results will save patients from unnecessary treatment with paclitaxel, which can have severe side effects with limited benefit.

Dr Lesley Walker, director of cancer information at Cancer Research UK, said: "This is an excellent example of how basic science can lead to discoveries that improve the treatment of patients. One of the Cancer Research UK is create the most targeted treatments with fewer side effects, and this is a fundamental step in achieving this - possibly customize the treatment of thousands of people suffering from cancer. "

New discovery of gene

In 1933, Franklin Delano Roosevelt presidency and began work on the huge chaos of a nation, he had inherited. Banks were closed and controls could not be cashed. The unemployment rate reached 25%, and agriculture fell apart. Foreclosure packages have been the country at an alarming rate.

The "New Deal", a set of economic recovery and reform programs, was immediately for the rescue of United States dollars and the people in office. Despite criticism at the time and today, the New Deal and the chance of aid, and has established programs such as Social Security Administration, Housing Authority and the Securities and Exchange Commission, which are still in our government.

Although perhaps not the Great Depression, it continues on a new set of ideals, non-discrimination, including laws, work and equal opportunities for women and minorities. Overall, it is an island rescue for Hanging by a thread-economic, they on the water, while the country the courage to "live as usual."

"In a broad sense, the concept of" New Deal "is a response to economic change, what's happening in our society," Jessie Williams, owner and founder of the clothing stores Edge of Urge said.
ART for a good cause: Jessie Williams from Edge of Urge developed the "New Deal", not only for the community of the hand of art, but to increase funding for Dream Art Center training.

Williams is currently the recycling of the year in a modern concept of the test, remember, Wilmington's nonprofit community, at a time when fiscal policy, in close collaboration fistedness. "People are still under evaluation, which is necessary in their private lives, and new creative methods to get what they want and need," she says. "It is important that in these crazy times, we must not forget about the community around us. If we have all our resources, we are all much better. This figure is power!"

Williams is no stranger to meeting in new opportunities. Edge of Urge opening in 2002 of a collection of his own designs, it has always been at the forefront of fashion. Your company is a combination of personal creations and fashion of the vision of Metro Designer discoveries. "I understand how difficult it is to himself in the market as a creator of man," she says. "I slowly but surely, in every seven years, company has become a springboard for young designers and creative work. I am not a doctor, saving lives every day, but I can my abilities and tools to a difference in peoples' opened new avenues in life. "

Business Outlook and your attention to the collection of funds has led to a version of "New Deal". "I meet every day, the artists want to make a difference in the world. The objective is to allow an outlet for designers to network man and share their art, and in the Community. It is only possible as an effort. Everyone has a chance to make a difference. [The "New Deal"] is an event for the Community in the Community. "

The result is a fund raiser, shows the sensitivity of taxes and innovative projects from 12 different fashionmistahs and fashionistas. "The theme of Fashion Show-utilitarianism and the need for more and more popular. We believe that this leaves much room for interpretation," said Williams. "As designers, we have many things to create, no matter what happens. It is a process of problem solving, and diversity. All work for this show is in response to the" New Deal of the need for a discussion, always fashionable, but the designer who infused each one-of-a-child-room with their own vision and capacity. Some parts are entirely on the resource or to find materials with several options, be taken into consideration. All the comment, which is necessary for fashion. "

When asked about fashion as a contribution to the art, Williams has much to contribute. "I think art is the expression," she says. "When I was little, I do something treasures on earth, which is not for most people. For me, a means of expression. I would like to do something together and small, to wear jewelry or a gift for mom or a friend to wear. Today, I still have a wealth of materials, which may have been neglected or not, for any reason. I like the challenge in the treasures of art and personal expression. Mode ... contains all the means to wear the heart on the sleeve. "

Your sense of recycling treasuress may explain why Williams chose DREAMS Center for Art Education is the case of recipients. DREAMS is a local art house, the mentoring relationship with artists and teachers on children with low incomes. The Center's mission, a "safe harbor" for school students and offers an alternative for fun only at home or hang on the roads. The program has a cause of the closeness and love Williams' heart for a while.

"Dreams of love was to discover years!" She says. "I do not know where I am today if I can not have the opportunity to be, art. I almost missed, but was fortunate to have the hand around me and give me a chance, as me, who I am today.

"I feel really happy for my training, experience and care by the year. I also know that there are still many more children, as is exactly like me who, by their hands, or with music with their bodies, I believe, their Saving Grace. We are very honored to work with dreams. "

The "New Deal" home market will be held May 9, from 1-7pm, at 3709 Oleander Drive in Hanover Haverty center of the old space. Besides the activities in the fields of art, design and other works, music is played by different groups: Thursday of the summer, Jane Beck experience Fayaway, Owl laws more, and the soldier J . minors. Similarly, Dan Brawley's Cucalorus Crew presents a selection of short films Indie. Most importantly, the dreams of teachers, implementation of free movement and conduct workshops for their students market patrons. DREAMS are created works of art at auction, with donations from artists and companies in the city. Includes three nights Soon Head Island.

At 7pm, in a tent donated by L & L Tent Rental, fashion begins at the Independence Mall parking. A performance of Rock Band and Guitar Hero Freezepop lights follow. "I feel Wilmington, should not be on tons and tons of fun, but what is more important for small, who are our future," said Williams.

Celera Corp. Q1 2009 Earnings Call Transcript

Hello, my name is niket and I will be your conference today. At this point, I would like to welcome all Celera First Quarter 2009 Earnings Conference Call. (Operator manual) I would like now to introduce Dr. David Speechly, Vice President of Corporate Affairs at Celera. Dr. Speechly you can begin your conference.

David Speechly, Ph.D.
Thank you very much, operator. Hello and thank you all for participation in the management Celera for the first quarter 2009 financial results, we in the early afternoon. Today, Kathy Ordoñez our Chief Executive Officer and Ugo DeBlasi our Chief Financial Officer and other leaders of Celera and Berkeley HeartLab.

During this call, the future statements about Celera business. Outlook end financial reports or advice for other reasons as conference calls or in our press releases. All the conclusions of this conference call about our expectations, beliefs, plans, objectives, assumptions or future events or performance are not historical facts are forward-looking statements. These reports are often but not always, using words and phrases, said that, expect, anticipate, estimate, believe, intend to, plan, predict, could, should and would. For example, talk of financial advice in 2009, financial conditions, product launches, permissions and time, or the future can be expected to yield, growth, industry ranking, plans and objectives of management and future economic conditions are forward-looking statements.

Foresight is not considered as guarantees of performance. They are subject to known and unknown risks and uncertainties could cause actual results significantly expenditure expressed or implied. Factors that lead to such differences are, but are not limited to, in our SEC.

We will also discuss the history and future statements, non-GAAP Financial Measures. This non-GAAP measure is not in compliance with all other full and GAAP and non-GAAP Financial Measures, by other companies. An approximation of U.S. GAAP and non-GAAP financial.

Please note that this call after the text of these comments are prepared in the Investor Relations website Celera.

First, Kathy Ordoñez and Ugo DeBlasi is thinking, Celera's performance during the quarter and we call for questions. Kathy.

Kathy Ordoñez
Thank you, David, and all afternoon. We had a solid first quarter of 2009 as sales of more than 15% over the same quarter the previous year, with 69% gross margin for the translation result in a growth of non-GAAP basis. We are at our collections and we are pleased with the appointment of Ugo DeBlasi as our Chief Financial Officer.

Many of you know, Ugo. With his knowledge of our profession and in close collaboration with us for many years as part of the Applera has a direct impact on Celera. We believe his experience and his financial and leadership are also in the future.

The first quarter was also a very productive period for us against a large number of scientific and economic development. All that our commitment to a leading provider of genetic tests are used routinely in customization Disease Management. Achieving this goal requires that we have a wide range of genetic tests for predisposition of individual prediction of disease and treatment decisions drive. We believe we have made good progress in the development pipeline with our own findings of its own as the variance of the ONP and KIF6 genes with other data to support their marketing. In addition, this quarter we have new results of an immunoassay for the detection of lung cancer in blood samples.

Road Food "warriors discovered document

MIAMI-best-selling authors Jane and Michael Stern have crisscrossed the country many times, for the best regional food for their "Road Food" Franchise.

There is no return route chaotic, city, blocked roads or endless highway they do not, within three to ten years, research of the highest expression to include the triple-Cheese Burger Patty, Apple scatter or New England Clam Chowder.

But even with all the write-CRED couple awarded a column for Gourmet Magazine and be heard weekly on public service broadcasting "The Splendid Table is not buy at home as the best Cuban sandwich, Conch Key Lime Pie Chowder or in southern Florida. Finally, there are so many candidates. But the star of that they have found the greatest examples of each in his next book, "500 things to eat before it is too late.

Your on-the-money comments It is hoped, on the Key Lime Pie on Quinn's, an elegant steak house in Ocean Drive's Park Central Hotel.

"The crust is graham crackers-fat on faith, its one-two punch is bitter sweet and brilliant," write the star that the accessories for the Key Lime Pie-crust with ginger on the snap Key West's Louie's Backyard, as well as versions in Key West Key Lime Pie Co. Joe's Stone Crab.

The pie at Joe's and tent is true. But what if Quinn's? A quick bite or two, and you begin, you must use the box star 'new book, taking into account the States. The secret?

"We use only the key lime fresh, never in the substance of the bottle," said Chief Jay Daigle. "And yes, there are some good butter in the crust.

The star of his own approaches, but also suggestions.

"We're just two people. Tripping Sometimes we just need a place, and it is much more. But if we leave armed with a list of advice from other people," says Michael.

He and Jane are both 62nd if not fly across the country, then jump in rental cars, so far the restaurants, they are tools for their own hybrid Lexus. They are not foreign, three or four breakfast or lunch in one day.

"If we do this, there was no Internet. People write us letters. Now we roadfood.com and men are constantly being proposed." You think, "the Cuban sandwich is great, let me tell you, a better place. "passionate people.

"Over 90 percent of the organizations that write to us about cost effective, informal, roll-your-Channel-up fare. We will really fight for what is regarded as the best barbecue, the best Fried Chicken, the best Key Lime Pie. In particular, regional differences. Someone who loves one in New York, Hot Dog in Chicago and can not even recognize what is there as in all hot-dog. "

The title of the star 'new book, published in the June 4th, could be an indication that the country pockets of specific culinary disappears, but like her, and tasting, feeling, more optimistic.

"Some of these foods are in danger, because of the nature of the homogenization is going on everywhere. But there are new foods that their way in the country," says Stern. "We have a very varied national cuisine. And it is impossible to undertake a codification of the kitchen. Tex-Mex, Italian-American. He was agitated, and can never imagine that the nature of the codification exercise that indicates that "this is the way to this court," which are in other countries. Here, everyone has his own, and it can be messy and chaotic, but it can do well. "