The discovery of a series of genes that are associated with increased risk of skin cancer, hepatitis B and susceptibility to radiation, have three different teams.
Scientists of the Institute for Cancer Research UK under Richard Murray, discovered that up to 70% of fatal cancers of the skin (melanoma) can be fired from a genetic mutation that leads cells to a cancer after exposure to excessive sun. The discovery may lead to more effective future tr
eatments targeted by drugs, was published in the journal "Cancer Cell" (cancer cells).
British researchers have identified the gene BRAF, from which often starts the chain of genetic changes leading to melanoma. Scientists know for certain gene already, but until now were not sure whether a cause or effect of cancer and is now established that the First case. Although melanoma represents a small percentage of skin cancers, responsible for most deaths.
Another scientific team from the University of Pennsylvania in the U.S. in the Vivian Tseoungk, identified a group of genes, around 1200, that affect how the human body reacts to radiation from the environment, often leading to cancer. According to the researcher is most likely to identify people who are more likely to have serious side effects from radiation exposure and to protect such by reducing the dose of radiation they receive.
Finally, a third scientific team from Japan has identified a number of gene mutations that appear to make people more sensitive towards chronic infection with hepatitis B. The discovery of researchers at the University of Tokyo, under the Giotsiro Kamatani, published in the journal "Nature Genetics .
Approximately 400 million people are suffering from chronic hepatitis B worldwide and 60% of cancers of the liver associated with the contamination. Japanese researchers compared the genes of patients with hepatitis B, people who do not have the infection and were able to identify 11 genetic mutations in a region containing the genes HLA-DPA1 and HLA-DPB1.
Although not the only cause of the hepatitis B infection, genetic factors seem to play an important role. The Japanese researchers hope the findings will assist in new drug therapies.
Scientists of the Institute for Cancer Research UK under Richard Murray, discovered that up to 70% of fatal cancers of the skin (melanoma) can be fired from a genetic mutation that leads cells to a cancer after exposure to excessive sun. The discovery may lead to more effective future tr
eatments targeted by drugs, was published in the journal "Cancer Cell" (cancer cells).British researchers have identified the gene BRAF, from which often starts the chain of genetic changes leading to melanoma. Scientists know for certain gene already, but until now were not sure whether a cause or effect of cancer and is now established that the First case. Although melanoma represents a small percentage of skin cancers, responsible for most deaths.
Another scientific team from the University of Pennsylvania in the U.S. in the Vivian Tseoungk, identified a group of genes, around 1200, that affect how the human body reacts to radiation from the environment, often leading to cancer. According to the researcher is most likely to identify people who are more likely to have serious side effects from radiation exposure and to protect such by reducing the dose of radiation they receive.
Finally, a third scientific team from Japan has identified a number of gene mutations that appear to make people more sensitive towards chronic infection with hepatitis B. The discovery of researchers at the University of Tokyo, under the Giotsiro Kamatani, published in the journal "Nature Genetics .
Approximately 400 million people are suffering from chronic hepatitis B worldwide and 60% of cancers of the liver associated with the contamination. Japanese researchers compared the genes of patients with hepatitis B, people who do not have the infection and were able to identify 11 genetic mutations in a region containing the genes HLA-DPA1 and HLA-DPB1.
Although not the only cause of the hepatitis B infection, genetic factors seem to play an important role. The Japanese researchers hope the findings will assist in new drug therapies.
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