The news was announced 5 days before and on 29 February. The news stated that Stephen Barr and his team from the University of Alberta in Canada, after studies found a gene that is able to block the spread of AIDS virus in the body and disease. The importance of the discovery are enormous, because it may mean the capability to manufacture a vaccine for the virus in the future ...
The professor and his team discovered a gene TRIM22, which has managed to prevent contamination of cell culture in the laboratory from HIV AIDS. It was when the gene in cells, the virus could not be replicated, and also prevented to go and infect other cells. This essentially means that even if an infected cell the virus stops spreading there, and not the rest of body.
In simple words, if researchers manage and develop the technique to be applicable to humans (ie to activate the gene in some way, even pharmaceuticals), then this would mean constructing physical defense against the virus, without the unpleasant side effects drugs or the manufacture of medicines will do the same job without having to be hazardous.
The researchers report that among other things, as many genes as humans have to protect the body from viruses and help to combat them, the gene has a strong preference in dealing with HIV AIDS.
The biggest problem scientists regarding the battle with the AIDS virus for years (and what it prevents than to build a successful vaccine) is that the virus mutate so easily be resistant against medicines made by time. With this gene, essentially found a new weapon that can do the job fighting the virus naturally.
The research scientists went one step further by trying to block the function of this gene in cells. This resulted in the cell to react to the virus but (as usual) the production of interferon, but the reaction was not the slightest effect. What does this mean that practically the gene is certainly a special relationship with HIV and AIDS need to address it. The body from which it seems has an own way to respond to the incursion of the virus. What we think eistimones is to replicate the function and mode of action of the gene TRIM22 with a drug.
Under investigation are open and two other "hot" questions:
"Why if the gene is located in the body of all people, in patients with AIDS is not working?"
And also:
"I can now activate this gene in these patients to take action?"
Search fee and the possibility of dealing and other viruses with the same gene.
Pending developments, therefore, very interesting ...
The findings were published in Public Library of Science Pathogens
The professor and his team discovered a gene TRIM22, which has managed to prevent contamination of cell culture in the laboratory from HIV AIDS. It was when the gene in cells, the virus could not be replicated, and also prevented to go and infect other cells. This essentially means that even if an infected cell the virus stops spreading there, and not the rest of body.
In simple words, if researchers manage and develop the technique to be applicable to humans (ie to activate the gene in some way, even pharmaceuticals), then this would mean constructing physical defense against the virus, without the unpleasant side effects drugs or the manufacture of medicines will do the same job without having to be hazardous.
The researchers report that among other things, as many genes as humans have to protect the body from viruses and help to combat them, the gene has a strong preference in dealing with HIV AIDS.
The biggest problem scientists regarding the battle with the AIDS virus for years (and what it prevents than to build a successful vaccine) is that the virus mutate so easily be resistant against medicines made by time. With this gene, essentially found a new weapon that can do the job fighting the virus naturally.
The research scientists went one step further by trying to block the function of this gene in cells. This resulted in the cell to react to the virus but (as usual) the production of interferon, but the reaction was not the slightest effect. What does this mean that practically the gene is certainly a special relationship with HIV and AIDS need to address it. The body from which it seems has an own way to respond to the incursion of the virus. What we think eistimones is to replicate the function and mode of action of the gene TRIM22 with a drug.
Under investigation are open and two other "hot" questions:
"Why if the gene is located in the body of all people, in patients with AIDS is not working?"
And also:
"I can now activate this gene in these patients to take action?"
Search fee and the possibility of dealing and other viruses with the same gene.
Pending developments, therefore, very interesting ...
The findings were published in Public Library of Science Pathogens
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